2014 Publications
Brust R, Haigney A, Lukacs A, Gil A, Hossain S, Addison K, Lai CT, Towrie M, Greetham GM, Clark IP, Illarionov B, Bacher A, Kim RR, Fischer M, Simmerling C, Meech SR, and PJ Tonge. 2014. Ultrafast Structural Dynamics of BlsA, a Photoreceptor from the Pathogenic Bacterium Acinetobacter baumannii. J. Phys. Chem. Lett. 5:220-224.
Cimica V, Dalrymple NA, Roth E, Nasonov A, and ER Mackow. 2014. An innate immunity-regulating virulence determinant is uniquely encoded by the Andes virus nucleocapsid protein. MBio. 5(1):e01088-13.
Chung LK, Philip NH, Schmidt VA, Koller A, Strowig T, Flavell RA, Brodsky IE, and JB Bliska. 2014. IQGAP1 is important for activation of caspase-1 in macrophages and is targeted by Yersinia pestis type III effector YopM. MBio. 5(4):e01402-14.
Dalrymple NA and ER Mackow. 2014. Virus interactions with endothelial cell receptors: implications for viral pathogenesis. Curr. Opin. Virol. 7:134-40.
DelGiorno KE, Tam JW, Hall JC, Thotakura G, Crawford HC, and AW van der Velden. 2014. Persistent salmonellosis causes pancreatitis in a murine model of infection. PLoS One. 9(4):e92807.
Doyle CR, Pan JA, Mena P, Zong WX, and DG Thanassi. 2014. TolC-dependent modulation of host cell death by the Francisella tularensis live vaccine strain. Infect. Immun. 82(5):2068-78.
Fukuto HS and JB Bliska. 2014. Editorial: Yersinia pestis survives in neutrophils and sends a PS to macrophages: bon appetit! J Leukoc Biol. 95:383-5.
Gao J and NS Sampson. 2014. A GMC oxidoreductase homologue is required for acetylation of glycopeptidolipid in Mycobacterium smegmatis. Biochemistry. 53:611-3.
Ivanov MI, Hill J and JB Bliska. 2014. Direct neutralization of type III effector translocation by the variable region of a monoclonal antibody to Yersinia pestis LcrV. Clin. Vaccine Immunol. 21(5):667-73.
Li HJ, Lai CT, Pan P, Yu W, Liu N, Bommineni GR, Garcia-Diaz M, Simmerling C, and PJ Tonge. 2014. A structural and energetic model for the slow-onset inhibition of the Mycobacterium tuberculosis enoyl-ACP reductase InhA. A. C. S. Chem. Biol. 9:986-93.
Mackow ER, Dalrymple NA, Cimica V, Matthys V, Gorbunova E, and I Gavrilovskaya. 2014. Hantavirus interferon regulation and virulence determinants. Virus Res. 187:65-71.
Matthys VS, Cimica V, Dalrymple NA, Glennon NB, Bianco C, and ER Mackow. 2014. Hantavirus GnT elements mediate TRAF3 binding and inhibit RIG-I/TBK1-directed beta interferon transcription by blocking IRF3 phosphorylation. J. Virol. 88:2246-59.
Pan P, Knudson SE, Bommineni GR, Li HJ, Lai CT, Liu N, Garcia-Diaz M, Simmerling C, Patil SS, Slayden RA, and PJ Tonge. 2014. Time-dependent diaryl ether inhibitors of InhA: structure-activity relationship studies of enzyme inhibition, antibacterial activity, and in vivo efficacy. ChemMedChem. 9:776-91.
Sheridan BS, Pham QM, Lee YT, Cauley LS, Puddington L, and L Lefrançois. 2014. Oral infection drives a distinct population of intestinal resident memory CD8(+) T cells with enhanced protective function. Immunity. 40:747-57.
Tam JW, Kullas AL, Mena P, Bliska JB, and AW van der Velden. 2014. CD11b+ Ly6Chi Ly6G- immature myeloid cells recruited in response to Salmonella enterica serovar Typhimurium infection exhibit protective and immunosuppressive properties. Infect. Immun. 82(6):2606-14.
Tan L, Parker KA and NS Sampson. 2014. A bicyclo[4.2.0]octene-derived monomer provides completely linear alternating copolymers via alternating ring-opening metathesis polymerization (AROMP). Macromolecules. 47(19):6572-6579.
Toledo A, Crowley JT, Coleman JL, LaRocca TJ, Chiantia S, London E, and JL Benach. 2014. Selective association of outer surface lipoproteins with the lipid rafts of Borrelia burgdorferi. MBio. 5(2):e00899-14.
Venkataraman K, Guja KE, Garcia-Diaz M, and AW Karzai. 2014. Non-stop mRNA decay: a special attribute of trans-translation mediated ribosome rescue. Front. Microbiol. 5:93.
Venkataraman K, Zafar H and AW Karzai. 2014. Distinct tmRNA sequence elements facilitate RNase R engagement on rescued ribosomes for selective nonstop mRNA decay. Nucleic Acids Res. 42:11192-202.
Wang H, Lu Y, Liu L, Kim SW, Hooker JM, Fowler JS, and PJ Tonge. 2014. Radiosynthesis and biological evaluation of a novel enoyl-ACP reductase inhibitor for Staphylococcus aureus. Eur. J. Med. Chem. 88:66-73.
Wang X, Parashar K, Sitaram A, and JB Bliska. 2014. The GAP activity of type III effector YopE triggers killing of Yersinia in macrophages. PLoS Pathog. 10(8):e1004346.
Wu L and NS Sampson. 2014. Fucose, mannose, and β-N-acetylglucosamine glycopolymers initiate the mouse sperm acrosome reaction through convergent signaling pathways. A. C. S. Chem. Biol. 9:468-75.
Yang M, Guja KE, Thomas ST, Garcia-Diaz M, and NS Sampson. 2014. A distinct MaoC-like enoyl-CoA hydratase architecture mediates cholesterol catabolism in Mycobacterium tuberculosis. A. C. S. Chem Biol. 9:2632-45.
Zhang Y, Mena P, Romanov G, and JB Bliska. 2014. Effector CD8+ T cells are generated in response to an immunodominant epitope in type III effector YopE during primary Yersinia pseudotuberculosis infection. Infect. Immun. 82:3033-44.